Helical Superstructure of Intermediate Filaments
نویسندگان
چکیده
منابع مشابه
Intermediate filaments
Intermediate filaments form a class of insoluble cytoplasmic filaments ofdimensions intermediate in size between those of microtubules (about 25 nm in diameter) and microfilaments (about 7 nm in diameter). Thus, they are generally known as intermediate-sized filaments (IF)' or 10-nm filaments. They have been identified in virtually all differentiated types ofcells and it seems possible that IF-...
متن کاملNeuronal intermediate filaments.
Neurofilaments (NFs) are the most abundant structural components in large-diameter myelinated axons. Assembled as obligate heteropolymers requiring NF-L and substoichiometric amounts of NF-M and/or NF-H, NF investment into axons is essential for establishment of axonal caliber, itself a key determinant of conduction velocity. Use of transgenic mice to increase axonal accumulation of NFs or to e...
متن کاملIntermediate filaments in smooth muscle.
The intermediate filament (IF) network is one of the three cytoskeletal systems in smooth muscle. The type III IF proteins vimentin and desmin are major constituents of the network in smooth muscle cells and tissues. Lack of vimentin or desmin impairs contractile ability of various smooth muscle preparations, implying their important role for smooth muscle force development. The IF framework ha...
متن کاملIntermediate filaments at a glance.
Eukaryotic cells feature two ubiquitous fibrous cytoskeletal polymers in their cytoplasm: F-actin and microtubules. A third fibrous polymer, intermediate filaments (IFs), appeared more recently in evolution (Fuchs and Cleveland, 1998; Erber et al., 1998). Two common traits define members of the family of IF proteins. First, these proteins exhibit a characteristic tripartite domain organization,...
متن کاملIntermediate Filaments on the Move
In most vertebrate cells, intermediate filaments (IF) 1 form a continuous structural network extending from the nuclear surface to the cell periphery. Their unique viscoelastic properties render them more resistant than either microtubules or microfilaments to deformation and other external physical stresses. Through a growing family of associated proteins (IFAPs), IF are now known to be connec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Physical Review Letters
سال: 2019
ISSN: 0031-9007,1079-7114
DOI: 10.1103/physrevlett.122.098101